Strains simulations & engineering

From the genome to the metabolic networks.


We usually start from whole-genome sequences: we reconstruct and annotate the genomic sequences from bacteria and unicellular eukaryotes such as yeasts and microalgae. We use the genome to reconstruct the metabolic pathways of these microbial species. The pathways are then used to simulate the microbes. The outcome of these tools are phenotype characterization (e.g. for probiotics), engineering of new metabolic pathways, productivity optimization. We also develop models for predictive microbiology (e.g. shelf-life modelling) and bioprocess applications (e.g. fermentation).

  • Simulating bacteria
  • A Systems Biology approach
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The microbiomes